How to setup Microsoft 365 on your computers and mobile devices


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If you are a Health Sciences Exchange user, do not use these instructions. Instead, please contact the HS Help Desk at (714) 456-3333 for support.

You can send and receive Microsoft 365 emails using any Modern Auth/OAuth-compatible email client. Clients that support OAuth can take advantage of security features such as Single Sign-on and Duo two-factor authentication.

Below is a list of the most popular clients along with their minimum system requirements, where applicable.

OIT cannot assist with the operating system or mail client upgrades.

We also recommend Outlook Mobile for iOS or Android, which you can download from your mobile device's app store.

Setup Guides